Graduate School Subjects

Graduate School Subjects

Common subjects

Subject Description
Pharmacology Special Lecture 1, 2 With the goal of learning about the development status and results of the pharmaceutical industry through new drug development, which is the core and ultimate goal of modern biotechnology, medical school professors (more than 30) are invited every week to provide education in connection with clinical and pharmaceutical research.
Pharmacology Seminar 1, 2 Comprehension and discussion of research papers to identify the latest research trends in graduate students’ major fields, and when necessary, knowledge acquisition is promoted by inviting experts in the field.
Pharmacology Seminar 3, 4 Graduate students who will be engaged in research in the biopharmaceutical field will develop the ability to identify recent research trends in the field, be familiar with research implementation methods, present research results, practice writing papers, and present professional knowledge in a seminar format.
Research Guide 1 – 6 In conjunction with each affiliated advisor and associate advisor, guidance is provided on thesis writing based on discussion of the research plan and results.

Majors

Subject Description
Laboratory Clerkship I Students in the integrated bachelor’s and master’s program (research pharmacists) attend and discuss research and thesis seminars in the advisor’s laboratory.
Laboratory Clerkship II Students in the integrated bachelor’s and master’s program (research pharmacists) attend and discuss research and thesis seminars in the advisor’s laboratory.
Special lecture on biochemistry Recent research results in biochemistry and molecular biology are selected by topic and are then introduced and discussed.
Special Topics in Pharmaceutical Microbiology Allows for students to discuss the latest knowledge and progress regarding microorganisms used in the production of pharmaceuticals, and in particular on plasmids, vectors, transformation, gene cloning, etc. as basic knowledge of genetic engineering.
Special lecture on medical molecular biology Allows for students to discuss the functions and interactions of various genes and proteins identified through human genome research, as well as cutting-edge drug development technologies such as new prevention methods and gene therapy at the molecular level. Discussions on the latest research trends and future utilization and development plans in the pharmaceutical field are held.
Special Topics in Antibiotic Chemistry Professors and students will lecture and discuss the latest knowledge on antibiotics used as medicines and newly discovered antibiotics, as well as their production mechanisms, resistance mechanisms, chemistry, and biosynthesis.
Topics in biopharmaceuticals Allows for students to discuss the general issues related to medicines currently being developed based on molecular and cell biology.
Special lecture on immunotherapy To help gain an overall understanding of immunology, the lecture will cover the cells and organs involved in the body’s immune response and examining each immune response, immune mechanism against pathogens, tumor immunology, and the immune response against tumors in detail
Special lecture on genetics and genomics research Lectures held on the major studies in genetics, latest research techniques, results, and research trends in gene replication, transcription, gene decoding, protein synthesis processes, molecular structure, evolution and interaction, and genome analysis techniques will be held. In particular, research and discussion on the application and trend of new drug development in gene and genome research will be held.
Special lecture on medicinal immunology Lectures on various types of immunotherapy, vaccines, etc. known so far, as well as on various immunological experimental methods.
Special Topics in Molecular Oncology Lectures on the characteristics of cancer cells, differences from normal cells, the cause of cancer, biochemical and molecular biological mechanisms of the carcinogenesis process, the function of oncogenes and carcinogenic inhibitory genes, cancer treatment and prevention strategies, and the biochemical mechanisms of various drugs used therein. In addition, through thesis presentations, the ability to familiarize and discuss recent trends in cancer research will be gained.
Subject Description
Special Lecture on Molecular Pharmacology and Lab This course covers mechanisms of drugs affecting the cardiovascular system and autonomic nervous system in relation to the activation of biologically active substance as well as characteristics of various active factors involved in the regulation of vascular tone in cardiovascular system, intracellular action mechanism, pathophysiologic significance, and application.
In this course, the students will also study the connection of body phenomenon occurring at cellular level, roles of autonomic nervous system, and influence to effects of biologically active substance based on theory and practice. The students will study pharmacokinetics and pharmacodynamics of loop diuretics widely used as auxiliary drug for edema and hypertension caused by heart, kidney, and liver abnormalities.
Clinical Pharmacokinetics and Lab The pharmacokinetic parameters of drugs are different for each individual. The drugs with narrow therapeutic range are ineffective at low blood level and cause side effects at high blood level. In this course, the students will determine the dose for each patient to maximize therapeutic effect and minimize side effect.
Drug Receptor Theory and Lab In this course, students will understand the concept of receptors as a primary information transmission process engaged in the regulation of biological phenomena. The students will also identify the types, targets, tissues, experimental methods, connections to physiological phenomena, and applications of receptors found in the body, as well as the current status and direction of research in related field.
Biochemical Pharmacology In this course, students will learn theories on the actions of drugs on living cells and cells, the relationship of these actions with the pharmacological effects of drugs.
Special Lecture on Molecular Pathophysiology This course investigates the pathological mechanism of diseases at the molecular level and covers the progress of cellular or tissue pathogen reaction based on interaction of molecules. In this course, the students will select and introduce the recent research results for each topic to understand different diseases from a molecular pathophysiological perspective.
Special Lecture on Therapeutic Protein Development Biomedicine refers to a high-molecular substances derived from living organisms, and it mainly involves therapeutic proteins. With high market growth rate of therapeutic proteins, many companies are jumping into the related market. This course provides an overview of the recent development of protein therapeutics and discusses the development process from industrial, academic, and regulatory perspectives.
Special Lecture on Biomedicine Mechanism This course covers the latest research trends, future applications, developments of advanced pharmacy, including the functions and interactions of various genes and proteins identified by human genome research, and new preventive methods at molecular level, and gene therapy. This course also focuses on antibiotics used in drugs, the latest knowledge on antibiotics, production mechanism, resistance mechanism chemistry, and biosynthesis. This course involves lecture and discussion by professor and students.
Special Lecture on Pharmacokinetics Part 1 covers the basic knowledge of pharmacokinetics. Part 2 builds on basic knowledge and reviews and discusses diseases or factors that affect the pharmacokinetics of drugs and recent articles on pharmacokinetics published in international journals.
Special Lecture on Latest Toxicology This course involves lecture and discussion by professor and students on the latest studies of toxic substances and toxic mechanism causing diseases, development of new drug used in treatment and prevention of diseases, development of disease prevention drugs, development of anti-aging agent, and development of substance for detoxifying and removing toxic substance, such as carcinogen.
Drug Metabolomics In this course, students will learn the molecular interaction, such as drug-receptor and drug-enzyme. This course covers molecular biology of drug metabolism, signaling pathway protein-nucleic acids interaction, and drug-induced gene regulation. The students will also learn and discuss the latest reports, research methods, and research results for analyzing the drug action in based on mechanism.
Endocrine Disrupting Chemicals This course covers understanding of cells and organs related to the body’s immune response and examines the immune response. This course also enhances understanding on immunology by studying the immune mechanism of pathogen, tumor immunology, and immune reaction to tumors.
Special Lecture on Drug Interaction Mechanism In this course, students will learn the clinical drug effects and side effects caused after administering different drugs simultaneously to a patient based on following items : 1. Pharmacologic effects and mechanisms 2. Clinical result evaluation 3. Practical implications 4. Integration 5. Other related drugs
Subject Description
Biosynthesis of Plant This course covers biosynthetic pathways of medicinal contents in plants and discusses the experimental techniques for studying the biosynthesis.
Special Lecture on Pharmaceutical Analysis I This course mainly focuses on the precise quantitative theory of chemical evaluation for pharmaceutical analytical chemistry. In this course, students will learn the theory of separation from various mixtures and the observation skills for physicochemical mathematical expressions.
Special Lecture on Pharmaceutical Analysis II In this course, students will learn the basic theory of Raman spectroscopy, learn how to use the instrument, build up application skills, and obtain and utilize the necessary data for identification and structure of the substances.
Pharmaceutical Formulation Analysis I This course describes essential methodologies for microanalysis of organic compounds, and this course mainly focuses on various derivatives and reactions.
Pharmaceutical Formulation Analysis II This course focuses on the practical applications of nuclear magnetic resonance spectroscopy for inspecting pharmaceutical products. The students will learn how to obtain substance structure-related information from PMR and CMR, and application of various techniques of 1-D and 2-D NMR.
Instrumental Analysis I This course covers the basic principles of chromatographs, simple theories, and instrumentation applications, by focusing on separation analysis.
Instrumental Analysis II This course covers practical application of spectrometry (Elemental analyzer, IR, NMR, UV, Mass) for basic theory of substance identification and structure estimation.
Active Substance Screening This course involves lecture and lab on the principles and applications of searching various active substances from herbal medicines.
Structure Analysis This course covers the analysis methods of various spectra used to determine the chemical structure of components isolated from herbal medicines.
Special Lecture on Herb Medicine and Natural Products This course shares the global trends and the latest information on pharmacognosy and discusses technologies applicable in the pharmaceutical industry. The students will also learn the origins and medicinal effects of herbal medicines.
Biologically Active Natural Substance Studies I This course introduces the pre-screening and screening methods for specific activities of natural products, isolation method of components by activity-guided fractionation, and method of identifying the structure. The students will also learn the animal cell culture methods for efficacy screening and plant tissue culture methods as part of methods to increase the yield of pharmaceutical components.
Biologically Active Natural Substance Studies II This course covers the process and research methods for pure isolation of organic compounds exhibiting physiological activities in natural products. The course mainly targets on carcinogens, anticancer substance, anti-inflammatory substance, contraceptives, antibiotics, radioimmune assays, affinity chromatography, prostaglandins, phytoalexines, plant hormones, and pheromones.
Special Lecture on Medical Chemistry This course covers theories of synthesis in organic compounds using organic chemistry unit reaction and provides overview on major, minor, or competitive reactions. In this course, the students will learn basic theories for the synthesis and development of sophisticated drugs such as pharmaceuticals, agricultural chemicals, fragrances, and chemicals./td>
Physical Organic Pharmaceutical Chemistry This course covers the reaction mechanisms of general organic chemical reactions based on the physical and chemical characteristics of existing organic chemical reactions such as substitution and elimination reactions.
Special Lecture on Organic Pharmaceutical Synthesis Chemistry This course covers catalyzed hydrogenation, dehydrogenation, reduction by metal hydride, related reactions, reduction by metals, oxidation by Cr and Mn compounds, oxidation by peracids, and halogenation.
Subject Description
Pharmaceutical Biomaterials This course covers synthetic polymers, such as polyethylene glycol, and biopolymer, including protein and polysaccharide, used as drug delivery materials. The materials are divided based on material characteristics (biodegradable polymer, water-soluble polymer, hydrogel) and structures (chain polymers and cross-linked polymers).
The students will learn the biomaterial’s structure, property, and interaction with drugs and will learn the actual examples to analyze the material functions for enhancing drug efficacy and reducing toxin. The course aims to help the students understand the various biological reactions triggered by administering the drug delivery agent to the body, and to foster the ability to predict and solve the potential side effects and toxicity by using materials in development of drug delivery agent.
Special Lecture on Macromolecular Drug Delivery A macromolecular drug refers to protein drugs, polysaccharide drugs, and genes used in disease treatment. For protein drugs, the students will learn about protein drug delivery systems related to chemical/physical binder technology, modifier technology, formulation and device technology. For polysaccharide drugs, the students will learn about oral formulation technology by chemical derivative. For gene drugs, the students will learn viral and non-viral delivery system. This course also covers cell delivery technology using genetically modified cell technology and protein delivery technology.
Special Lecture on Pharmaceutics This course examines absorption, distribution, metabolism, and excretion of drugs based on pharmacokinetics, and the students will solve pharmacokinetics mathematically to broaden their physical understanding of drugs. The students will be able to establish the administration plan for controlling dose and interval without direct human experiment. This course aims to secure the effectiveness, safety, and conveniences of drugs by delivering the drugs to the necessary parts quantitatively.
Biophysical Pharmacy NMR and X-ray crystallography are the two main methods for studying tertiary structure of proteins and nucleic acids, which are the main research subjects of biophysical pharmacy. Especially, NMR is rapidly developing these days, and it holds strengths in studying the structure of biomaterials in solutions. This course aims to help the students understand NMR-related knowledge essential for studying NMR-related biomaterial structures in graduate schools.
Special Lecture on Industrial Pharmacy This course covers production process and quality control of finished pharmaceutical products for each formula. This course also includes physical pharmaceutical theories related to production workshop design, workplace arrangement, principle and management of production instruments, and formulation design.
Special Lecture on Tissue-Specific Drug Transport This course covers actualization of tissue-specific drug transport by identifying the characteristics of drug receptors in tissue’s biomembrane. It especially reviews the latest discoveries in tissue-specific drug transport studies by focusing on the organs, such as brain and kidney, with polarized biomembrane, and tissues with altered biomembrane properties, such as tumors.
Special Lecture on Drug Transport The purpose of kinetics is to set the in vivo behavior of drugs with a relatively simple model and predict the blood concentration, half-life period, metabolic rate, excretion rate, and accumulation amount quantitatively. The purpose of this course is as follows : 1. Identify the instrument for in vivo drug phenomenon 2. Regulate dose, interval, and formula 3. Develop more effective and more stable drug.
Special Lecture on Biopharmaceutics This course covers application of drugs and in vivo events, including drug absorption, in vivo distribution metabolism, and excretion-related instrument, pharmaceutical factors, drug administration route and in vivo distribution, bioavailability, and rational administration plan.
Special Lecture on Biologically Active Substance Delivery System In this course, the students will learn physicopharmaceutical theories, manufacturing, assessment, and application of system, interaction between biologically active substance and system, and interaction between system and biomarkers to be considered in designing the biologically active substance delivery system.
Classification Subject Description
Required Major Special Lecture on Clinical Pharmacy In this course, the students will learn the clinical characteristics of newly released and licensed drugs, drugs with additional indications, and drugs with new safety information.
Clinical Insurance Pharmacy In this course, the students will learn about the theories of the health insurance system, benefit standards and deductibles, brief understanding of medical fees, understanding of relative value scores and legal information, and benefit standards for each disease and drug.
Special Lecture on Social Pharmacy In this course, the students will foster their skills and social leadership skills to discuss on the latest topics related to medicine, analyze the relevant issues, and find the solutions.
Drug System Studies In this course, the students will learn about health care systems and health coverage, and they will also learn about various national regulatory policies regarding effectiveness, safety, and cost from drug development to final use.
Major Elective Special Lecture on Tumor Pharmacotherapy In this course, the students will learn about the cause, diagnosis, and stages of cancer, classification and mechanisms of non-drug and drug therapies, and abnormal reaction.
Pharmaceutical Care for Cardiovascular Diseases This course covers epidemiology, pathophysiology, cause, diagnosis, non-drug therapy, drug therapy, drug classes, treatment guidelines, and group treatment plans for cardiovascular diseases. This course also covers use of device as a non-drug therapy for cardiovascular diseases and examines the end-of-life decision by cardiovascular patients.
Pharmaceutical Care for Digestive Diseases This course covers the key theories for drug treatment of digestive system diseases. The course requires the students to provide patient-oriented drug treatment, collect scientific evidences, and reflect patient needs as a drug treatment expert. The students will also learn the process of establishing the treatment assessment plan in consideration of patient needs and advising and monitoring the adequate treatment method.
Pharmaceutical Care for Renal Diseases In this course, the students will learn acute and chronic kidney disease and complications based on electrolyte and fluid therapy. The students will also learn the personalized therapy and organ transplantation based on kidney function.
Clinical Biostatistics This course covers theories and experiments of clinical biostatistics utilized in health practice and research field.
Research Methodology In this course, the students will learn pharmaceutical literature analysis techniques required for practice of evidence-based pharmacy. The students will also learn the research methodologies for writing papers based on understanding of research designs (systematic literature reviews, experimental studies, observational studies, etc.).
Pharmacoeconomics In this course, the students will learn the concepts of economic evaluation methods (cost minimization analysis, cost-effectiveness analysis, cost-utility analysis, cost-benefit analysis) to assess the value of new drugs. The students will also learn the practical techniques, including modeling, cost and performance measurement, and sensitivity analysis.
Pharmaceutical Industry In this course, the students will learn the industrial characteristics of drugs, the latest drug development trend, the characteristics of drug supply by pharmaceutical companies under the health insurance system, and drug promotion and consumer communication methods.
Managed Care Pharmacy This course examines the current status of pharmacist services in local and hospital pharmacies and explores strategies for developing expertise of pharmacist and managing pharmacies to prepare for future environmental changes.
Drug and Society Seminar This course analyzes and explores the social value of medicines and discusses the goals to be pursued in the development, distribution, and use of new medicines based on these values. This course also discusses the professional ethics and social behavior in the field of drug-related professions.