Chaemin Im
Chaemin Im
전공Physical Pharmacy, Drug Delivery Science
연락처
031-881-7181
chaemin@cha.ac.kr
학력
- 2007.03 – 2011.02 조선대학교 약학과 (약학사)
- 2011.03 – 2017.02 중앙대학교 약학과 (약학박사)
경력
- 2023 – 현재: 차의과학대학교 약학대학 조교수
- 2022-2023: 중앙대학교 약학대학, 연구교수
- 2018-2022: University of North Carolina at Chapel Hill, 박사후연구원
논문
- 연구분야
- 본 연구실은 Polymer 혹은 Lipid를 기반으로 하는 약물전달시스템을 개발하는 연구를 주로 진행하고 있습니다. Chemical drug 뿐만 아니라 gene materials 및 protein/peptide delivery 쪽으로도 다양한 연구를 진행합니다.
- C. Lim 1, D. Hwang 1, Y. Mostafa, J.D. Ramsey, G. Dotti, Sokolsky, A.V. Kabanov, High-Dose Paclitaxel and its Combination with CSF1R Inhibitor in Polymeric Micelles for Chemoimmunotherapy of Triple Negative Breast Cancer, Nano Today, 51 (2023), 101884 (Impact factor: 18.9).
- P. Husni, Y. Shin, H Jeon, E.S. Lee, Y.S. Youn, C.D. Poon, C. Lim *, K.T. Oh * (Corresponding author), Development and characterization of pH-responsive nanocarriers for chemo-photothermal combination therapy in glioblastoma treatment, Journal of Controlled Release, 359 (2023), 52 (Impact factor: 11.5).
- Y Shin, M Kim, C. Lim *, K.T. Oh *, (Corresponding author) RNA-Seq-guided triple-combination nano-system of gold nanocluster, quercetin, and docetaxel for ultimate synergistic photothermal-chemotherapy against MDR tumor, Nano Today, 50 (2023), 101862. (Impact factor: 18.9).
- P. Husni, C. Lim *, K.T. Oh * (Corresponding author), Tumor microenvironment stimuli-responsive lipid-drug conjugates (LDCs) for cancer treatment, International Journal of Pharmaceutics, (2023), 122942.
- C. Lim 1, Y. Shin 1, K. Kang, P. Husni, D. Lee, S. Lee, H. Choi, E.S. Lee, Y.S. Youn, K.T. Oh, Effects of PEG-Linker Chain Length of Folate-Linked Liposomal Formulations on Targeting Ability and Antitumor Activity of Encapsulated Drug, International Journal of Nanomedicine, (2023), 1615.
- C. Lim 1, D. Lee1, M. Kim, S. Lee, Y. Shin, J. D. Ramsey, H. Choi, E.S. Lee, Y.S. Youn, K.T. Oh, Development of a sorafenib-loaded solid self-nanoemulsifying drug delivery system: Formulation optimization and characterization of enhanced properties, Journal of Drug Delivery Science and Technology, 82 (2023), 104374.
- C Lim, J Koo, K.T. Oh, Nanomedicine approaches for medulloblastoma therapy, Journal of Pharmaceutical Investigation, 10 (2022), 00597.
- C Lim, Y Shin, S Lee, S Lee, M Lee, B Shin, K.T. Oh, Dynamic drug release state and PEG length in PEGylated liposomal formulations define the distribution and pharmacological performance of drug, Journal of Drug Delivery Science and Technology, 9 (2022), 103825.
- C. Lim 1, T. Dismuke 1, D. Malawsky, J.D. Ramsey, D. Hwang, V.L. Godfrey, A.V. Kananov, T.R. Gershon, M. Sokolsky, Enhancing CDK4/6 inhibitor therapy for medulloblastoma using nanoparticle delivery and scRNA-seq-guided combination with sapanisertib, Science advances, 8 (2022) eabl5838 (Impact factor: 14.9).
- C. Lim, J.D. Ramsey, D. Hwang, S. Teixeira, C.D. Poon, J.D. Strauss, M. Sokolsky, A.V. Kabanov, Drug-dependent morphological transitions in spherical and worm-like micelles define stability and pharmacological performance of micellar drugs, Small, 18 (2022), 2103552 (Impact factor: 15.1).
- C. Lim, J.K. Kang, C.E. Jung, T. Sim, J. Her, K. Kang, E.S. Lee, Y.S. Youn, H.-G. Choi, K.T. Oh, Preparation and Characterization of a Lutein Solid Dispersion to Improve Its Solubility and Stability, AAPS PharmSciTech, 22 (2021) 169.
- T. Sim1, C. Lim, N.H. Hoang, Y. Shin, J.C. Kim, J.Y. Park, J. Her, E.S. Lee, Y.S. Youn, K.T. Oh, An On-Demand pH-Sensitive Nanocluster for Cancer Treatment by Combining Photothermal Therapy and Chemotherapy, Pharmaceutics. 12 (9) (2020) 839.
- C. Lim, W.R. Won, J. Moon, T. Sim, Y. Shin, J.C. Kim, E.S. Lee, Y.S. Youn, K.T. Oh, Co-delivery of d-(KLAKLAK)2 peptide and doxorubicin using a pH-sensitive nanocarrier for synergistic anticancer treatment, Journal of Materials Chemistry B, 7 (2019) 4299-4308.
- C. Lim, J. Moon, T. Sim, W.R. Won, E.S. Lee, Y.S. Youn, K.T. Oh, A nano-complex system to overcome antagonistic photo-chemo combination cancer therapy, Journal of Controlled Release, 295 (2019) 164-173 (Impact factor: 11.5).
- C. Lim, J.K. Kang, W.R. Won, J.Y. Park, S.M. Han, T.N. Le, J.C. Kim, J. Her, Y. Shin, K.T. Oh, Co-delivery of D-(KLAKLAK)(2) Peptide and Chlorin e6 using a Liposomal Complex for Synergistic Cancer Therapy, Pharmaceutics, 11 (2019) 293.
논문