남훈식

남훈식 교수

전공약품분석학, 오믹스학

연락처 약품분석학, 오믹스학

학력

2016 서울대학교 제약학과 (약학사)
2024 서울대학교 약학과 (약학박사)

경력

2024 – 2025 University of Michigan, 박사후연구원
2026 – 현재 차의과학대학교 약학과 조교수

연구분야 본 연구실은 질량분석(MS)과 핵자기공명분광(NMR) 등 첨단 분석기술을 기반으로 대사체학(Metabolomics)을 중심으로 한 다중오믹스(Multi-omics) 연구를 수행합니다. 대사체학, 전사체학, 유전체학, 단백체학 데이터의 AI 기반 통합 분석을 적용하여 암 및 난치성 질환의 바이오마커 탐색과 신규 치료 표적 발굴을 목표로 합니다. 세포·동물·임상시료 수준의 다층적 접근을 통해 정밀의학 기반 진단 및 치료 전략 개발에 기여하고자 합니다.

논문

Nguyen TH, Mai XL, Nguyen TTM, Nam H, Lee JY, Park S. “Epigenetically-controlled CEBPB regulates kidney cancer tumorigenesis via GPD1L-mediated ether lipid synthesis”. Cell Death & Disease. 2026 Jan 22.
Nam H*, Yu G*, SI Ahn*, Nam S. “Mechanical Regulation of Metabolism, Epigenetics, and Their Crosstalk”. npj Biomedical Innovations. 2026 Jan 16;3(1):5.
Koh JH*, Park S*, Kang M, Park JI, Lee J, Cho H, Kim JE, Kim D, Li M, Nam H, Park S, Kim HJ, Kim DK, Lee H. “Altered acetate metabolism and signaling in IgA nephropathy: An integrated gut microbiome and glomerular spatial transcriptome analysis”. Frontiers in Immunology. 2025;16:1665585.
Cho H*, Nam H*, Kim H-E, Kim JE, Park JI, Park J, Kim YC, Lee JP, Kim DK, Joo KW, Kim YS, Kim B-S, Park S, Lee H. "Gut microbiome and metabolite signatures for predicting acute kidney transplant rejection: A prospective study". Scientific Reports. 2025 Dec 29;15(1):44709.
Kim D, Nguyen TT, Moon Y, Kim JM, Nam H, Cha DS, An YJ, de Guzman AC, Park S. “Time-Resolved Evaluation of L-Dopa Metabolism in Bacteria-Host Symbiotic System and the Effect on Parkinson's Molecular Pathology”. Small Methods. 2025 Mar;9(3):2400469.
Nam H*, Lee W*, Lee YJ, Kim JM, Jung KH, Hong SS, Kim SC, Park S. “Taurine Synthesis by 2-Aminoethanethiol Dioxygenase as a Vulnerable Metabolic Alteration in Pancreatic Cancer”. Biomolecules & Therapeutics. 2024 Dec 5;33(1):143–154
Nam H*, Kim D, Jin X, Park S. “Metabolic determinants of leukemia onset variability in genetically homogeneous AKR mice”. Biochemical and Biophysical Research Communications. 2024 Jun 11:150257.
Kim JE*, Nam H*, Park JI, Cho H, Lee J, Kim HE, Kim DK, Joo KW, Kim YS, Kim BS, Park S, Lee H. “Gut Microbial Genes and Metabolism for Methionine and Branched-Chain Amino Acids in Diabetic Nephropathy” Microbiology Spectrum. 2023 Apr 13;11(2):e02344-22.
Nam H*, Hong SS*, Jung KH*, Kang S*, Park MS*, Kang S, Kim HS, Mai VH, Kim J, Lee H, Lee W, Park S. “A Serum Marker for Early Pancreatic Cancer with a Possible Link to Diabetes” JNCI: Journal of the National Cancer Institute. 2022 Feb 1;114(2):228-34.
Kim ER*, Kwon HN*, Nam H, Kim JJ, Park S, Kim YH. “Urine-NMR Metabolomics for Screening of Advanced Colorectal Adenoma and Early Stage Colorectal Cancer” Scientific Reports. 2019 Mar 18;9(1):4786.

저서/역서/편서

특허

아스프로신을 포함하는 췌장암 진단용 바이오마커 및 이의 이용, 등록번호 10-23567676, 등록일자 2022-01-24
Biomarkers for Diagnosis of Pancreatic Cancer Comprising Asprosin, and Use Thereof, 미국 출원번호 18265677 (PCT/KR2021/004403)